Controlled delivery systems of cellulose matrix for oxytetracycline: In vitro dissolution
Abstract Microfibrillated cellulose (MFC) has recently been explored as a novel nanostructured system for controlled drug delivery. The present study examines the releasing behavior and antibacterial efficacy of cellulose (CC) and tempo-oxidized- microfibrillated cellulose (TO-MFC) loaded with oxytetracycline at three different physiological pH (2.1, 6.8 and 9.0). The releasing mechanism from cellulosic matrix was assessed […]